STUDIES OF EXPERIMENTAL CALCIUM OXALATE STONE

Protein-crystal Interactions in Calcium Oxalate Kidney Stone Formation

We have studied the ability of urinary molecules in altering the precipitation of kidney stone-related calcium oxalate monohydrate (COM) crystals and correlated the resulting morphologies with those of idiopathic COM kidney stones. We found that weakly acidic but highly glycosylated polyelectrolytes (Tamm Horsfall protein (THP), fetuinA, hyaluronic acid) do not significantly affect crystallizat...

Overweight and Obesity: Risk Factors in Calcium Oxalate Stone Disease?

Introduction. Several studies showed an association of overweight and obesity with calcium oxalate stone disease (CaOx). However, there are no sufficient data on the influence of body weight on the course of the disease and the recurrence rate. Patients and Methods. N = 100 consecutive stone formers with pure CaOx were studied. Different parameters were investigated. According to the BMI, patie...

Association between Dietary Diversity Score and Nutrient Adequacy in Patients with Calcium Oxalate Kidney Stone

Background: Nephrolithiasis is a global health problem that is growing exponentially in the developed and developing countries. This study aimed to determine the dietary diversity score (DDS) and its association with nutrient adequacy in patients with calcium oxalate kidney stone. Methods: The present cross-sectional study was conducted on 276 male patients with calcium oxalate kidney stone. Th...

SUMMARY SUMMARY The role of dicarboxylic acid on oxalate metabolism in experimental hyperoxaluric and Calcium oxalate stone forming rats and isolation and characterisation of oxalate

Use of a calcium tracer to detect stone increments in a rat calcium oxalate xenoplantation model

The majority of urinary stones have been observed to grow by circular increments in the clinic and in animal studies. However, the mechanism of stone formation has not yet been elucidated. Marking the stone at specific time-points during the growth of the stone is likely to enable the clarification of the mechanisms behind lithogenesis. The objective of this study was to evaluate the role and e...